Insights from

Nobel Laureates, for scientists everywhere

Michael Brown

Michael Brown

Michael S. Brown received a B.A. degree in Chemistry in 1962 and an M.D. degree in 1966 from the University of Pennsylvania. He was an intern and resident at the Massachusetts General Hospital, and a postdoctoral fellow with Dr Earl Stadtman at the National Institutes of Health. In 1971, he moved to the University of Texas Southwestern Medical Center in Dallas, where he rose through the ranks to become a professor in 1976.

He is currently Paul J. Thomas Professor of Molecular Genetics and Director of the Jonsson Center for Molecular Genetics at UT Southwestern. Dr Brown and his long-time colleague, Dr Joseph L. Goldstein, together discovered the low-density lipoprotein (LDL) receptor, which controls the level of cholesterol in blood and in cells. They showed that mutations in this receptor cause familial hypercholesterolemia, a disorder that leads to premature heart attacks in one out of every 500 people in most populations.

They have received many awards for this work, including the US National Medal of Science and the 1985 Nobel Prize for Medicine or Physiology.

Michael Brown lecture video – Cambridge
Michael Brown

Michael Brown lecture video – Cambridge

What drives a good scientist?
Michael Brown

What drives a good scientist?

Michael S. Brown Lecture Video
Michael Brown

Michael S. Brown Lecture Video

Is it difficult to balance work and family life?
Michael Brown

Is it difficult to balance work and family life?

How do you know if you’re cut out for research?
Michael Brown

How do you know if you’re cut out for research?

How do you pick your first independent research topic?
Michael Brown

How do you pick your first independent research topic?

What was your first research job?
Michael Brown

What was your first research job?

What advice would you give a young scientist searching for a research topic?
Michael Brown

What advice would you give a young scientist searching for a research topic?

Did you ever feel uncertain about your choice of career?
Michael Brown

Did you ever feel uncertain about your choice of career?

What’s the most important career decision for a scientist?
Michael Brown

What’s the most important career decision for a scientist?

What does it take to be a successful scientist?
Michael Brown

What does it take to be a successful scientist?

Who should advocate for scientists?
Michael Brown

Who should advocate for scientists?

What do you think of the emphasis placed on impact factors?
Michael Brown

What do you think of the emphasis placed on impact factors?

Highlights Video: Michael Brown
Michael Brown

Highlights Video: Michael Brown

What kept you motivated during low points in your research?
Michael Brown

What kept you motivated during low points in your research?